Best Supplements for Diabetes to Help Lower Blood
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What Is Diabetes?

Diabetes is a disease that occurs when your blood glucose, also called blood sugar, is too high. It is a chronic metabolic disease that occurs when the body doesn't produce enough insulin or can't use the insulin it produces properly.

Insulin is a hormone made by the pancreas that helps glucose get into your cells to be used for energy. If you have diabetes, your body doesn’t make enough—or any—insulin or doesn’t use insulin properly. Glucose then stays in your blood and doesn’t reach your cells.

Diabetes not only causes increased blood sugar, but also causes complications in multiple organs, such as cardiovascular disease, kidney disease, neuropathy, etc.

Best Supplements for Diabetes to Help Lower Blood

Exercising regularly, eating a balanced fiber-rich diet, and managing stress can help lower blood sugar levels. At the same time, blood sugar levels can also be regulated through supplements.

1、Berberine

Berberine is a chemical found in some plants like European barberry, goldenseal, goldthread, Oregon grape, phellodendron, and tree turmeric. Berberine is a bitter-tasting and yellow-colored chemical. It might help strengthen the heartbeat, It is mainly used to potentially help lower blood sugar, improve cardiovascular health, reduce oxidative stress, and lower cholesterol. as well for its anti-diarrheal, anti-inflammatory, and anti-cancer effects

2、Bitter Melon

Bitter melon is linked to lowering the body's blood sugar. This is because the bitter melon has properties that act like insulin, which helps bring glucose into the cells for energy.
Insulin-like properties: Bitter melon contains polypeptide-p, or p-insulin, a protein that acts like insulin and helps glucose enter cells for energy.

Glucagon suppression: Bitter melon may lower blood sugar by suppressing glucagon levels.
Nutrient retention: Bitter melon may help the body retain nutrients by preventing them from being converted to glucose and released into the bloodstream.
Bitter melon isn't an approved treatment or medication for prediabetes or diabetes despite the evidence that it can manage blood sugar.

3、Cinnamon

Cinnamon may help lower blood sugar levels, and some studies suggest that it can be especially beneficial for people with high blood sugar. Cinnamon contains natural compounds that mimic insulin, which can help keep blood glucose levels stable. 

Cinnamon exhibits characteristics that mimic insulin, such as the activity of biologically active substances to activate insulin receptor kinase, increasing glucose uptake, autophosphorylation of the insulin receptor, and glycogen synthase activity [1]. It has been stated that cinnamon increases glycogen storage by affecting glycogen synthesis activity [2]. In a study, it was found that the cinnamon peel extract would increase insulin sensitivity and raise glucose intake [3]. Water-soluble components of cinnamon have been found to enhance the effectiveness of the insulin signaling pathway [4].

4、Chromium

Chromium is an essential mineral that helps the body regulate blood sugar levels.
Chromium picolinate is the most effective form of chromium supplementation. Studies have found that supplements containing 200–1,000 mcg of chromium picolinate daily can improve blood glucose control. Chromium picolinate has also been shown to reduce insulin resistance and may help reduce the risk of cardiovascular disease and type 2 diabetes.

References

1. Baker W. L., Gutierrez-Williams G., White C. M., Kluger J., Coleman C. I. Effect of cinnamon on glucose control and lipid parameters. Diabetes Care2008;31(1):41–43. doi: 10.2337/dc07-1711. [PubMed] [CrossRef] []
2. Broadhurst C. L., Polansky M. M., Anderson R. A. Insulin-like biological activity of culinary and medicinal plant aqueous extracts in vitro. Journal of Agricultural and Food Chemistry2000;48(3):849–852. doi: 10.1021/jf9904517. [PubMed] [CrossRef] []
3. Hong J., Yang G., Kim Y. B., Eom S. H., Lew J., Kang H. Anti-inflammatory activity of cinnamon water extract in vivo and in vitro LPS-induced models. BMC Complementary and Alternative Medicine2012;12(1, article no. 237) doi: 10.1186/1472-6882-12-237. [PMC free article] [PubMed] [CrossRef] []
4. Imparl-Radosevich J., Deas S., Polansky M. M., et al. Regulation of PTP-1 and insulin receptor kinase by fractions from cinnamon: implications for cinnamon regulation of insulin signalling. Hormone Research in Paediatrics1998;50(3):177–182. doi: 10.1159/000023270. [PubMed] [CrossRef] []
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